Abstract
Background Exsanguination and coagulopathy remain one of the leading causes of preventable trauma related death [1]. Low ionised calcium levels have been associated with hypotension and increased mortality [2]. Blood product contains citrate that acts as a calcium chelating agent. We hypothesized that trauma patients are at risk of hypocalcaemia and blood products given to resuscitate them would reduce serum Calcium concentration, and therefore affect 30-day mortality.
Highlights
Exsanguination and coagulopathy remain one of the leading causes of preventable trauma related death [1]
A retrospective cohort analysis was performed on all major trauma patients who had received early blood product in the Emergency Department of a single London Major Trauma Centre over a one year period (January 2013 – January 2014)
Ionised calcium levels were taken from venous blood gases from before and after blood product had been transfused
Summary
Exsanguination and coagulopathy remain one of the leading causes of preventable trauma related death [1]. Low ionised calcium levels have been associated with hypotension and increased mortality [2]. Blood product contains citrate that acts as a calcium chelating agent. We hypothesized that trauma patients are at risk of hypocalcaemia and blood products given to resuscitate them would reduce serum Calcium concentration, and affect 30-day mortality
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