A retrospective analysis of the factors related to pediatric acute respiratory distress syndrome′s prognosis

Abstract

Objective To investigate the prognostic factors of pediatric acute respiratory distress syndrome(pARDS), according to pARDS criteria from the 2015 Pediatric Acute Lung Injury Consensus Conference. Methods Clinical data of 69 cases with pARDS in PICU of Beijing Children′s Hospital affiliated to Capital Medical University from January 2009 to December 2015 were retrospectively analyzed. Results Among the 69 cases of pARDS, there were 13 cases with mild ARDS, 19 cases with moderate ARDS and 37 cases with severe ARDS.Seventeen pARDS were dead in PICU, including 2 mild pARDS, 3 moderate pARDS and 12 severe pARDS, and 14 pARDS of them were female, 3 pARDS were male.Gender and chronic complication were related to the outcomes of pARDS, and the difference was significant(P<0.05). The mortality of pARDS with chronic complication was up to 69.23%.Duration of mechanical ventilation was related to PICU hospital stay and total length of hospital stay (correlation: 0.324, 0.181, P<0.01). Duration of mechanical ventilation was also related to weight(correlation 0.491, P<0.01), and weight was a protective factor. Conclusion pARDS is one of the most critical diseases in PICU with low morbidity and high mortality, the mortality of pARDS in this study is 24.64%.Female or chronic co-morbidities pARDS may have poor prognosis.Duration of mechanical ventilation determines the PICU length of stay and total hospital length of stay, and weight is the protective factor of the duration of mechanical ventilation. Key words: Acute respiratory distress syndrome; Children; Prognosis