A retrospective analysis of the causes of an adverse outcome in COVID-19 and HIV coinfection in the stage of secondary diseases

Abstract

The increased incidence of COVID-19 and HIV coinfection and the changes in the structure of HIV infection mortality during the pandemic necessitate an analysis of the causes of adverse outcomes in co-infection. Objective. To retrospectively analyze deaths in patients with COVID-19 and HIV coinfection in the stage of secondary diseases. Subjects and methods. The investigation involved the medical records of 56 patients with laboratorily confirmed COVID-19 and HIV infection who were hospitalized in January to December 2021. Results. A retrospective analysis of the medical reports showed that bilateral polysegmental pneumonia of mixed etiologies was the cause of death in the majority cases of COVID-19 and HIV coinfection in the stage of secondary diseases. Along with pneumonia, multiple opportunistic diseases and conditions, which aggravated the course of the underlying disease, were identified in these patients. Various somatic diseases are one of the reasons for the severe course of the coinfection. Conclusion. Stage IVB HIV infection was diagnosed in the majority of deaths. Bilateral polysegmental pneumonia of mixed etiologies was the most common cause of death in patients with COVID-19 and HIV coinfection in the stage of secondary diseases.