A retrospective analysis of cerebral venous sinus thrombosis-a series of 25 cases

Abstract

Objectives: To explore the character of Cerebral Venous Sinus Thrombosis (CVST), and to improve the early diagnosis and treatment of such a disease. Methods: Retrospective analysis of the ­patient ages, risk factors, clinical presentations, imaging characters and treatment of 25 CVST cases. Results: The most common age coverage of CVST attacks is from 18 to 45, the most common risk factors include female oral contraceptive (32%) and post-delivery or post-abortion (20%). The most common presentation is headache (80%), followed by paralysis (44%) and seizure (40%). Neuroimaging shows that transverse sinus is the most commonly affected sinus, followed by superior sagittal sinus. Low molecular heparin is effective to CVST and the prognosis of most patients is good. Conclusion: The diagnosis of CVST should be considered in young patients with recent unusual headaches or with stroke-like symptoms, in patients with intracranial hypertension, and in patients with hemorrhagic infarcts. To make a definite diagnosis and treat the patients in time, Enhanced MRI+MRV or Enhanced CT+CTV should be performed immediately, and if necessary, DSA should be performed.