Abstract

The most common cause of pyogenic infection of the skin and soft tissues in children is Staphylococcus aureus, a fast-emerging problem due to its accompanying significant cost and morbidity. The popularity of herbal medications has increased due to the search for cheaper and more accessible alternatives. However, data is still lacking to back up these claims. In this research work the main aim to increase the activity of neem against bacteria by incorporating flower extraction of African marigold. As both leave extraction of neem and flower extraction of marigold has potent inhibition properties against Staphylococcus aureus, a gram positive bacteria, so dual action can be achieved and the inhibition properties also get stimulated. Here the methanolic exaction of both plants were taken in an identical manner and incorporate in a culture of Staphylococcus aureus and check the zone of inhibition for neem extraction as well as neem and marigold combination extraction. The result of this combination shows dramatically increase in prohibition as compare to single neem extraction. So, the conclusion is that the combination therapy of Tagetes erecta L. and Azadirachta indica can increase the property of prohibition against gram positive bacteria.

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