Abstract
Background: Knee Osteoarthritis is considered as the leading cause of the disability in almost all over the world after age of 40. Almost about 54 percent people will end up in knee osteoarthritis in old age. Awareness of non-pharmacological treatment for knee osteoarthritis is more in practice in European as well as in Asian countries. Physical therapy, Ultrasound therapy, Otago exercises etc. are the treatments that are available for conservative management as well as preventive measure of knee Osteoarthritis.
 Methodology: Subjects with knee osteoarthritis with grade II to III on Kallgren and Lawrence classification will be included in the study N = 52. Two groups each of 26 will be allocated randomly as group A who will receive ultrasound treatment with Otago exercises control group and group B who will receive ultrasound treatment with zingiber Cassumunar based gel and Otago exercises as experimental group. The Western Ontario and McMaster University Osteoarthritis Index (WOMAC), VAS, star excursion balance test will be performed before and after the treatment after 2 weeks with single blind procedure.
 Objective: This research will examine the effect of treatment with Zingiber Cassumunar based gel applied by means of phonophoresis with ultrasound therapy in knee osteoarthritis patients with Randomized control trial.
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