Abstract

Aza-heterocyclic compounds have been known for their rich bioactivity characteristics which have been widely applied in many fields. Typically, pyrrolidine derivatives can inhibit the growth of strains of P. falciparum resistant to chloroquine. This articlepresents the research results on the synthesis of the heterocyclic compound N-aryl azacycloalkane from an alkyl halide and aniline derivatives under microwave conditions with the reaction time reduced by 20 times and the reaction efficiency doubled.

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