Abstract
We are grateful for the comments of Dr Jones and colleagues. We were aware of one case report by Rosaeg et al. [1] as well as the study by Nikkola et al. [2] that involved six patients. Both the case report, as well as the study, showed some benefit of using fentanyl patient-controlled analgesia for pain relief in labour. We felt it was not appropriate to make a conclusion on the use of fentanyl PCA for labour analgesia on the basis of studies that included only seven patients, but we admit we should have included those studies in our editorial. Regarding the use of fentanyl or remifentanil for labour analgesia, we think it is too early to suggest either is superior over the other and agree that further large studies are needed to establish the efficacy as well as the safety of these drugs.
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