Abstract
A method which has been developed for the satisfactory estimation of procaine in whole blood avoids the loss of procaine which was apparent in methods where blood proteins were precipitated by use of trichloroacetic acid. Approximately 85 per cent of the added procaine was constantly recovered by this method from test samples of blood and the procedure was considered to be satisfactory for determining concentrations of procaine m patients’ blood The peak concentration of procaine m blood twenty minutes after the infiltration of procaine (2.06-3.7 gm) varied from 0 7 ¼g to 50 ¼g. per gram of blood m the patients studied
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