Abstract

M-FISH (multiplex fluorescent in situ hybridization) is a multichannel channel chromosome imaging technique that allows the color discrimination of human chromosomes. Although M-FISH facilitates the visual detection of chromosome rearrangements, the success of this technique largely depends on the accuracy of the pixel-by-pixel classification. In this paper, we present a new method that enhances the classification ratio based on a region based decorrelation stretch transform. Utilizing the decomposition of the multichannel image into homogenous regions, the classification results improved after the application of the decorrelation stretch transform. Fifteen M-FISH images were used to test our method. To quantitatively estimate the enhancement we have used a Bayes pixel-by-pixel classifier and an improvement of 12.28% is achieved.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.