Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is prevalent in Danish swine herds. In July 2019, PRRSV‐1 was detected in a PRRSV‐negative boar station and subsequently spread to more than 38 herds that had received semen from the boar station. Full genome sequencing revealed a sequence of 15.098 nucleotides. Phylogenetic analyses showed that the strain was a recombination between the Amervac strain (Unistrain PRRS vaccine; Hipra) and the 96V198 strain (Suvaxyn PRRS; Zoetis AH). The major parent was the 96V198 strain that spanned ORFs 1–2 and part of ORF 3 and the minor parent was the Amervac strain, which constituted the remaining part of the genome. The virus seems to be highly transmissible and has caused severe disease in infected herds despite a high level of genetic identity to the attenuated parent strains. The source of infection was presumable a neighbouring farm situated 5.8 km from the boar station.
Highlights
Porcine reproductive and respiratory syndrome virus (PRRSV) has since its first appearance in the beginning of the 1990s been one of the major health challenges in pigs production
The samples were tested for antibodies against PRRSV using a commercial ELISA (IDEXX PRRS X3 Ab Test)
One of the samples tested positive for PRRSV and the boar station was immediately put under trade restrictions
Summary
Porcine reproductive and respiratory syndrome virus (PRRSV) has since its first appearance in the beginning of the 1990s been one of the major health challenges in pigs production. According to figures from the Danish SPF society, approximately 35 % of the Danish pig herds are positive for antibodies to PRRSV, but the prevalence of serological positive herds are declining (www.spfsus.dk). The strains clustering in the other clade are up to 12 % different from the “Porcilis-like” viruses and include the first PRRSV-1 strain isolated in Denmark in 1992 (Kvisgaard et al, 2013b). Several breeding companies are supplying semen to Danish sow herds; the largest supplying semen to more than 860,000 of the Danish production sows This breeding company consists of 14 boar stations, where four are defined as PRRSV seropositive and 10 are PRRSV seronegative. Despite that the outbreak is not fully investigated, we find it appropriate to submit this rapid outbreak report with focus on the genetic composition and the epidemiology of the new PRRSV strain with the primary aim to alert countries that import living pigs from Denmark
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