Abstract

To the Editor: An important medical advancement during the last 3 decades has been the development of accurate but noninvasive blood pressure monitoring devices. The successful application of such technology has lead to growing recognition that identifying elevated blood pressure variability (BPV) across a wide range of time scales may be useful in predicting poorer health outcomes. Thus, with great interest we read the article by Matsui et al1 showing that day-by-day BPV was lower in patients treated with an angiotensin II receptor blocker/calcium channel blocker combination compared with those treated with an angiotensin II receptor blocker/diuretic combination. This study raises the exciting possibility of potential methods for treating elevated BPV. In light of treatment possibilities, …

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