Abstract
Background: Cervical cancer metastasizes commonly to the bone, lungs, liver and the supraclavicular lymph nodes. Rare sites of metastasis the brain, breast, paraspinal muscles, duodenum and heart have been reported. Case report: A 53-year-old postmenopausal woman presented to our facility with a one-month history of vaginal bleeding. She was found to have an exophytic cervical mass on pelvic examination. She was managed as a case of stage IIIB cervical cancer. Histology revealed Squamous Cell Carcinoma type. She had radiotherapy and was symptoms free. She represented 3 months later with visual disturbance, headache and vomiting. She was found to have metastatic lesion to her brain. She survived for 3 months and 3weeks after first treatment. Conclusion: The prognosis of cervical cancer patients with brain metastases is frequently poor with median survival of only a few months such as in this case who survived 3 months and 3 weeks after first treatment. Only few reports have incidences of long-term, disease-free survival in these patients.
Highlights
Worldwide, the incidence and mortality from cervical cancer are second only to breast cancer, and in parts of the developing world, cervical cancer is the major cause of death in women of reproductive age.[1]
Hematogenous metastases occur in 12% of the cases with the common sites including
Choriocarcinoma is the most known gynecological malignancy that frequently metastasizes to the brain and it accounts for 35% of all brain metastasis in gynecological malignancies.[7]
Summary
The incidence and mortality from cervical cancer are second only to breast cancer, and in parts of the developing world, cervical cancer is the major cause of death in women of reproductive age.[1]. CASE REPORT A 53-year-old P6+0, postmenopausal woman presented to the gynaecological clinic of the Lagos University Teaching Hospital, Lagos on the 22/7/2010 with one-month history of postmenopausal vaginal bleeding. She had a history of watery vaginal discharge and mild lower abdominal pain radiating to the right leg Her general and systemic exams were within normal limits. After a thorough clinico-radiologic workup, it was staged as FIGO stage IIIB moderately differentiated Squamous Cell Carcinoma of the cervix. She was referred to the Radiotherapy unit. She was optimized with steroids but never came out of coma and died a week after readmission
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