Abstract

Down syndrome is the most common chromosomal abnormality encountered in humans, and it is caused by the presence of a third copy of chromosome 21, whether whole or merely a portion. Some of the conditions encountered more frequently in patients with Down syndrome are atresia (esophageal, duodenal, or small bowel), annular pancreas causing small bowel obstruction, imperforate anus, and Hirschsprung disease.

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