Abstract

Thyrotoxic periodic paralysis is a sporadic form of hypo-kalemic periodic paralysis and it is most commonly presents as sudden onset weakness in the proximal muscles. It is a disorder most commonly seen in Asian men which is characterised by abrupt onset of hypo-kalemia and paralysis and it is primarily affects lower extremities and is secondary to thyrotoxicosis. It is due to an intracellular shift of potassium induced by thyroid hormone sensitisation of Na/K ATPase rather than depletion of total potassium. The absence of a family history, male predilection and, presentation in second to fourth decade of life and signs of thyrotoxicosis and sinus tachycardia help in the diagnosis of the disorder. The age of onset is later and corresponded with age of incidence of thyrotoxicosis. It is very essential to diagnose TPP early and treat appropriately.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.