A rare coexistence of Kaposi s sarcoma and myelodysplastic syndrome in an immunocompetent patient A fortuitous association

Abstract

Kaposi's sarcom is an angiogenic tumor related to the Human Herpes Virus 8 . Its association with myelodysplastic syndrome had been rarely reported in the literature. Herein, we relate a case of coexistence of KS and MDS in a human immunodeficiency virus negative female patient, which is to our knowledge the fourth reported in the literature. Some data suggest that viral agents might be involved in the pathogenesis of MDS. The HHV8 is a virus with tropism for hematopoietic cells and expression of transforming viral genes that may affect cell proliferation and thus cause the trigger of myelodysplastic disorders. However, other studies on larger populations are necessary to determine the causal correlation between these two disorders.