A rare clinical case report of recurrent angiolymphoid hyperplasia with eosinophilia of hand treated by intralesional steroids following surgical excision: when a traditional therapy is still up to date.

Abstract

Abstract Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon idiopathic benign vascular disorder. Angiolymphoid hyperplasia with eosinophilia most often affects the head and neck, with involvement of other areas such as the hands occurring seldom. ALHE may affect people of any colour; however it is more common among Asians. Mostly, it affects young to middle-aged women presenting as fleshy/plum-coloured pruritic nodules and papules. The histological examination corresponds dense inflammation predominantly lymphocytes, forming aggregate and reactive follicles with germinal centre with many proliferative capillaries intermingled with the inflammatory cells along with eosinophils. A 21 year old female presented with distinct and coalescent erythematous nodular lesion in the right forearm since 5 months. The histopathological study was consistent with ALHE. Intralesional corticosteroid injections were performed monthly for six months and complete remission was accomplished. The goal of this rare case report is to notice and consider this rare clinical picture, review and analyze various diagnostic methods, differential diagnoses and treatment modalities.