A rare clinical case of uterine cancer with a congenital malformation of the genital organs

Abstract

Endometrial cancer is one of the most common options malignant neoplasms of the female reproductive system. At the same time, in the general structure of female oncopathology, cases of this disease in patients with developmental anomalies of the genital organs are extremely rare. When studying scientific publications, only 26 described clinical cases of uterine cancer in patients with genital malformations were found. The article presents a clinical case of endometrioid carcinoma in a 75-year-old woman with a duplication of uterus. Based on clinical performance, ultrasound investigation results, magnetic-resonance imaging and histological studies of endometrial scrapings was diagnosed duplication of uterus with endometrial cancer IB (cT1вNхМ0), G2 (morphological type endometrioid carcinoma). With this pathology, surgical treatment is considered as the most effective way to fight uterine cancer, in some cases combined with other methods. Both laparotomic and laparoscopic interventions are recommended, provided that pelvic and lumbar lymph node dissection can be performed according to indications. The operation was carried out in the amount of laparotomy, B2 type modified radical hysterectomy, with C3 pelvic lymph node dissection, omentectomy. The result of the postoperative histological examination confirmed the preoperative diagnosis. The postoperative period was without specific findings. The presented rare clinical case demonstrates necessity to give careful attention to patients with a congenital malformation of the genital organs. Timely diagnosis and diagnosis verification will allow for adequate treatment, which will affect the prognosis of survival. At the same time, the prognosis is largely determined by the stage of the process, the depth of the invasive lesion, and the histological type of the tumor.