Abstract
Gangliocytic paraganglioma (GP), a rare tumour that arises most frequently from the periampullary area, is considered to be a benign neoplasm with a potential for lymphatic spread. Distant metastases are rare [1]. We report a case of a 51 year old female who presented with abdominal pain, anaemia and melaena. Endoscopy, push enteroscopy and biopsy revealed a periampullary neuroendocrine tumour. Immunohistochemistry of the pancreatic duodenectomy specimen demonstrated a duodenal gangliocytic paraganglioma with no lymph node metastases. We review the literature on this rare tumour and the current treatment protocol.
Highlights
Gangliocytic paraganglioma (GP) is an uncommon tumour of the gastrointestinal tract with majority of cases arising in the duodenum [2]
We report a case of a 51 year old female who presented with abdominal pain, anaemia and melaena
We report a case of duodenal GP which has been treated with pancreaticoduodenectomy
Summary
Gangliocytic paraganglioma (GP) is an uncommon tumour of the gastrointestinal tract with majority of cases arising in the duodenum [2]. Other reported sites include the jejunum, pylorus, oesophagus, pancreas and appendix [3]. GP is generally benign with a low potential for lymph node and distant metastases. We report a case of duodenal GP which has been treated with pancreaticoduodenectomy
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