A Rare Cause of Diabetes Insipidus in Children: Langerhansian Histiocytosis

Yousra El Boussaadni,Kaoutar Ettoini,Mohamed Aggouri,Abdellah Oulmaati

doi:10.15342/ijms.7.272

Yousra El Boussaadni, Kaoutar Ettoini + Show 2 more

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https://doi.org/10.15342/ijms.7.272

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Abstract

Diabetes insipidus is a disease in which large volumes of dilute urine (polyuria) are excreted, We report the observation of a 2-year-old child who presents with stagnation in weight with polyuria polydipsia of diabetes insipidus, the cause of which is Langerhansian histiocytosis. Through this work, we highlight the clinical, paraclinical, evolutionary and therapeutic aspects of this affection.

Highlights

Diabetes insipidus (DI) is defined by an inability to retain free water and is due either to an insufficient release of antidiuretic hormone (ADH, called vasopressin), by the hypothalamus (= central diabetes insipidus - DIC), or to a resistance of the kidney to DHA (= nephrogenic diabetes insipidus), clinically diabetes insipidus is manifested by polyuria polydipsia
We report an observation of a 2-year-old child who consults for polydipsia polyuria and for whom the investigations revealed Langerhans’-cell histiocytosis (HL)
Usually, after the discovery of a polyuria-polydipsia it is first necessary to eliminate diabetes through a urine test strip, to measure the urinary osmolarity and propose a restriction test to distinguish between the DIC and the nephrogenic ID

Summary

A Rare Cause of Diabetes Insipidus in Children

Yousra El Boussaadni a , Kaoutar Ettoini a , Mohamed Aggouri b , Abdellah Oulmaati a a Pediatrics department, University Hospital Center, Faculty of Medicine and Pharmacy, University of Abdelmalek Essaadi, Tangier, Morocco. b Neurosurgery department, University Hospital Center, Faculty of Medicine and Pharmacy, University of Abdelmalek Essaadi, Tangier, Morocco.

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