Abstract
The antiphospholipid syndrome (APS) is characterized by the occurrence of venous or arterial thrombosis or of specific pregnancy morbidity, in the presence of laboratory evidence of antiphospholipid antibodies. APS was rarely seen in our clinical practice as a cardiologist. In this case, a 26-year-old man was admitted with acute peripheral arterial occlusion and ST-segment elevation myocardial infarction. He was undergone aspiration thrombectomy and right aorta-popliteal bypass surgery. During medical treatment ischemic stroke was determined. Vascular thrombosis affecting more than two organs, distinguishes the case from others. It shows that we should keep in mind APS, when extensive vascular thrombosis are seen in the clinical practice. Learning objective: Acute coronary syndromes seen in the clinical practice are caused by atherosclerosis more often than not. The antiphospholipid syndrome (APS) is one of a rare cause of acute coronary syndromes. This case is a brief review of the APS.
Highlights
The antiphospholipid syndrome (APS) is characterized by the occurrence of venous or arterial thrombosis or of specific pregnancy morbidity, in the presence of laboratory evidence of antiphospholipid antibodies
The Sapporo APS classification criteria were replaced by the Sydney criteria in 2006 [1]
Based on the most recent criteria, classification with APS requires one clinical and one (IgG and/or IgM anticardiolipin in moderate or high titer, antibodies to ß2-glycoprotein I of IgG or IgM isotype at a titer >99th percentile, Lupus anticoagulant activity detected according to published guidelines) laboratory manifestation [1]
Summary
The antiphospholipid syndrome (APS) is characterized by the occurrence of venous or arterial thrombosis or of specific pregnancy morbidity, in the presence of laboratory evidence of antiphospholipid antibodies. Syndrome (APS); Venous Thromboembolism (VTE); Acute peripheral arterial occlusion A 26-year-old man, who was diagnosed with left lower extremity deep venous thrombosis two weeks ago, was seen in the emergency department of our hospital because of right lower extremity pain.
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