A rare case report of hyaline vascular variant of Castleman\\\'s disease

Abstract

Castleman's disease, is a heterogenous spectrum of lymphoproliferative disorder also known as angiofollicular lymph node hyperplasia or giant lymph node hyperplasia, offers a diagnostic dilemma enriched with histological differences. Its manifestations, range from localized to systemic manifestation with progression to fatal disease involving multiple organs. It has 3 histological types- hyaline vascular variant (HVCD), plasma cell variant (PCCD) and mixed hyaline vascular and plasma cell variant. Clinically it can be classified as unicentric and multicentric. Here we report a case of unicentric Castleman disease in a 55 year old woman who presented with a swelling in the posterior aspect of the neck which was radiologically diagnosed as lipoma and histologically to proven to be a unicentric hyaline vascular type of Castleman's disease.