Abstract
Lymphomas are solid tumours of the immune system accounting for 14% of all head and neck malignancies. Non-Hodgkin lymphomas (NHL) are a heterogeneous group of lymphoproliferative disorders originating in B cells, T cells or natural killer T-cells. They have a vast array of clinical presentations and histological findings which can make diagnosis difficult. Lymph nodes, spleen, and liver are common sites of NHL. Extranodal soft tissue manifestation of NHL is a rare presentation of all lymphomas with a common occurrence in the geriatric population. Prevalent NHL is diffuse large B cell lymphoma which has significant clinical, morphological, and molecular heterogeneity leading to difficulty in timely diagnosis and treatment, and usually denotes an advanced stage. Here we throw light on primary skeletal muscle lymphoma-diffuse large B cell type, in an 81-year-old female patient mimicking cellulitis. It is vital to differentiate lymphoma from other entities to avoid perplexity in management.
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