A Rare Case of Pyogenic Granuloma in the Tooth Extraction Socket.

Yosuke Iijima,Ryutaro Kawano,Miki Yamada,Takahiro Kaneko,Leona Kashimata,Norio Horie,Nami Nakayama,Shunsuke Hino,Darko Macan

doi:10.1155/2021/5575896

Yosuke Iijima, Ryutaro Kawano + Show 7 more

Open Access

https://doi.org/10.1155/2021/5575896

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Abstract

Pyogenic granuloma (PG) refers to a common, acquired, benign, and vascular tumor that arises in tissues such as the skin and mucous membranes. However, it is extremely rare for PG to arise from an empty socket after tooth extraction. Herein, we describe a rare case of PG that arose from the empty extraction socket of the second molar adjacent to a dentigerous cyst of the left mandibular wisdom tooth in a 57-year-old man. The patient's second molar was extracted during the same procedure in which the wisdom tooth and cyst were removed. Subsequently, at 42 days after surgery, an exophytic mass was found in the socket of the second molar. An excisional biopsy was performed, and the histopathological diagnosis was PG. Since the PG recurred 90 days after the surgery, a complete excision with bone curettage was performed. During the 12 months of follow-up, there has been no recurrence observed. In conclusion, as tooth extraction is a routine dental practice, clinicians should be aware that PGs can also develop from an extraction socket.

Highlights

Pyogenic granuloma (PG) refers to a common, acquired, benign, and vascular tumor that arises in tissues such as the skin and mucous membranes [1]
We present a rare case of PG that arose from a tooth extraction socket of the tooth that was adjacent to a dentigerous cyst, which was extracted at the same time as the removal of the cyst
CD34, erythroblast transformation-specific-related gene (ERG), and WT-1 were positive for endothelial cells, with Ki-67 positivity found in approximately 5% of the epithelial cells (Figure 6)

Summary

Introduction

Pyogenic granuloma (PG) refers to a common, acquired, benign, and vascular tumor that arises in tissues such as the skin and mucous membranes [1]. The oral mucosa is a common site for PG, it is extremely rare for PG to arise from an extraction socket [6, 7]. In this case report, we present a rare case of PG that arose from a tooth extraction socket of the tooth that was adjacent to a dentigerous cyst, which was extracted at the same time as the removal of the cyst

Case Report

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Discussion