Abstract
A rare case of papillary carcinoma in thyroglossal cyst
Highlights
Thyroglossal duct cysts (TGDC) are the most common anomaly in the development of the thyroid gland, which constitutes 70% of midline masses in childhood and in adults about 7% [1]
Skeletal muscles were seen outside the cyst wall- The histopathological features were consistent with Thyroglossal Cyst with Papillary carcinoma thyroid
The epithelial lining of the cyst varies with location. Those that form near the tongue are lined by stratified squamous epithelium and those away are lined by pseudo stratified ciliated columnar epithelium and variable amounts of thyroid tissue may remain in the cysts
Summary
Thyroglossal duct cysts (TGDC) are the most common anomaly in the development of the thyroid gland, which constitutes 70% of midline masses in childhood and in adults about 7% [1]. A 45 year old female presented with swelling in front of neck of three months duration. USG Neck: Solid lesion with cystic component was seen. Solid component measuring 18x14 mm with specks of calcification, cystic component measuring 10x8 mm CT Scan of Neck (Plain and Contrast): An ill-defined irregular heterogeneous soft tissue lesion was seen having both solid and cystic component with calcification and enhancement in infrahyoid region indicating Thyroglossal Cyst with Malignant Transformation. Cut surface showed grey white well circumscribed lesion with mucoid areas. Skeletal muscles were seen outside the cyst wall- The histopathological features were consistent with Thyroglossal Cyst with Papillary carcinoma thyroid. Fig-A: Cut section showing grey white well circumscribed lesion with mucoid areas in the cyst. Follow up: On six month follow up with USG neck normal thyroid echo texture was seen with no significant abnormality and no evidence of nodal metastasis
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