Abstract
NFMAs are benign tumors that do not produce any biologically active hormones and exceed 10 mm (0.39 in) in size. Although NFMAs are benign in origin, mass effects may lead to serious clinical symptoms such as visual impairments, chronic headache, and pituitary insufficiency. The authors describe a 51-year-old woman who had a NFMA (35 × 24 × 25 mm). The vision was reduced to 7/10 in the both eyes. A transnasal transsphenoidal surgery was performed and the tumor was successfully resected. Postoperatively, the patient had visual (9/10) and headache improvement. This case highlights a rare presentation of non-functioning pituitary macroadenoma.
Highlights
The prevalence of pituitary tumors has been reported to be as high as 94 ± 19.3 cases per 100,000 population [1]
Pituitary tumors can be classified on the basis of their size, and this has been of considerable interest to the neurosurgeon
They have been classified into microadenomas (10 mm size) and giant pituitary adenomas (>40 mm size) [4]
Summary
The prevalence of pituitary tumors has been reported to be as high as 94 ± 19.3 cases per 100,000 population [1]. Most of these tumors are histological benign and represent 10% - 12% of all intracranial neoplasms [2] [3]. Pituitary tumors can be classified on the basis of their size, and this has been of considerable interest to the neurosurgeon. If a pituitary adenoma makes hormones it is called functional. Non-functioning pituitary macroadenomas (NFMAs) are common tumors of the anterior pituitary and are the most frequent indication for pituitary surgery [6]-[8]. (2014) A Rare Case of Non-Functioning Pituitary Macroadenoma (NFMA). We recently treated a patient who had a pituitary macroadenoma treated successfully by endoscopic transnasal transsphenoidal approach
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