Abstract

Dried thyme, black pepper and honey are widely used worldwide. However, systemic allergic reactions to these substances are rarely reported. Here we report a 45-year-old case with multiple severe anaphylaxis to thyme, black pepper, honey and wasp, that occurred at different times. Her reactions to thyme, black pepper and wasp were IgE-mediated as confirmed with skin prick tests and/or serology. It was not possible to determine the underlying etiology of her honey allergy. Still, with her history and the risk of systemic reactions with bee secretions and/or pollen protein content of honey, she was advised not to consume any traces of the causative foods and informed about bee avoidance.

Highlights

  • We report a case with IgE-mediated anaphylaxis due to thyme (Thymus vulgaris), black pepper (Piper nigrum) and wasp (Vespula vulgaris), and possible pollinator and/ or pollen protein-induced anaphylaxis due to honey

  • Dried thyme and black pepper are widely used as spice and seasoning

  • Black pepper and bee venom were proven to be IgE related by skin rests and/or specific IgE levels

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Summary

Introduction

We report a case with IgE-mediated anaphylaxis due to thyme (Thymus vulgaris), black pepper (Piper nigrum) and wasp (Vespula vulgaris), and possible pollinator and/ or pollen protein-induced anaphylaxis due to honey.CASE PRESENTATIONA 45-year-old female patient was referred to our clinic with history of recurrent anaphylaxis that had last occurred about a year ago. We report a 45-year-old case with multiple severe anaphylaxis to thyme, black pepper, honey and wasp, that occurred at different times. Black pepper and wasp were IgE-mediated as confirmed with skin prick tests and/or serology.

Results
Conclusion
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