Abstract

A wide variety of neuropsychiatric manifestations have been reported with COVID-19. We present a case of a 45-year-old man who developed significant hypersomnia and hypersexual thoughts following COVID-19 illness. Further evaluation did not reveal any other infection, structural brain disease, or stroke, leading us to consider Kleine–Levin syndrome as a diagnosis of exclusion. However, a confirmed diagnosis of this syndrome cannot be made on initial presentation, and its formal diagnosis requires recurrence of symptoms. Although relapses of this syndrome are known to be triggered by viral illnesses, no primary occurrences have been reported with COVID-19 to date.

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