Abstract

A Rare Case of Acute Pancreatitis Caused by Hepatitis B Virus Underwent Deceased Donor Liver Transplantation

Highlights

  • Acute pancreatitis (AP) can complicate the course of viral hepatitis, especially in cases of acute liver failure (ALF) [1,2]

  • It is of interest that these patients’ mortality is not found to be significantly different from patients without this complication. This is likely because AP is usually not severe, and survival is more dependent on the severity of the ALF

  • The patient required immediate improvement for liver dysfunction; we performed an open drainage. This was the first case report of a deceased donor liver transplantation (DDLT) for a patient with ALF caused by hepatitis B virus (HBV) and complicated with AP

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Summary

Introduction

Acute pancreatitis (AP) can complicate the course of viral hepatitis, especially in cases of acute liver failure (ALF) [1,2]. AP invariably complicates persistent organ failures caused by cytokine cascades. These cascades result in a systemic inflammatory response syndrome during the early phase. We will describe the first case report of a DDLT for a patient with ALF caused by the hepatitis B virus (HBV) and complicated by the presence of AP. Two weeks following the DDLT, the patient’s AST and ALT levels suddenly elevated and a CT examination revealed a walled-off necrosis (WON) caused by AP between the stomach and pancreas (Figures 3A and 3B). The patient’s liver function gradually improved after the drainage He left the intensive care unit on the 35th day after the DDLT. He is in rehabilitation to improve his physical strength

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