A rare case of a retroperitoneal enterogenous cyst with in-situ adenocarcinoma

Jeffrey T Lordan,Robin L Jones,Nariman D Karanjia,James G Woodland,Stefano De Sanctis,Gary Middleton,Neville Menezes

doi:10.1186/1477-7819-5-113

Jeffrey T Lordan, Robin L Jones + Show 5 more

Open Access

https://doi.org/10.1186/1477-7819-5-113

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Abstract

BackgroundRetroperitoneal enterogenous cysts are uncommon and adenocarcinoma within such cysts is a rare complication.Case presentationWe present the third described case of a retroperitoneal enterogenous cyst with adenocarcinomatous changes and only the second reported case whereby the cyst was not arising from any anatomical structure.ConclusionThis case demonstrates the difficulties in making a diagnosis as well as the importance of a multi-disciplinary approach, and raises further questions regarding post-operative treatment with chemotherapy.

Highlights

BackgroundWe present a patient with a retroperitoneal enterogenous cyst that contained adenocarcinoma cells presenting in adulthood
Retroperitoneal enterogenous cysts are uncommon and adenocarcinoma within such cysts is a rare complication.Case presentation: We present the third described case of a retroperitoneal enterogenous cyst with adenocarcinomatous changes and only the second reported case whereby the cyst was not arising from any anatomical structure
We present a patient with a retroperitoneal enterogenous cyst that contained adenocarcinoma cells presenting in adulthood

Summary

Background

We present a patient with a retroperitoneal enterogenous cyst that contained adenocarcinoma cells presenting in adulthood. Histology reported an invasive mucinous cystadenocarcinoma with clear circumferential margins and due to the nature of stratified columnar epithelium (figure 2) and high CA 19.9, it was considered to be of pancreatic or biliary origin. This conclusion was not entirely satisfactory due to the lack of specificity of CA 19-9 as a mucinous tumour marker. Within 3 weeks of surgical excision, the patient developed back pain radiating down the right lower limb His performance status deteriorated greatly, preventing the administration of palliative chemotherapy He died of metastatic disease, 6 weeks following resection of the cyst

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Conclusion