A rare case of a pathologic fracture of the talus due to a solitary plasmacytoma

Abstract

Plasma cell dyscrasias are a group of diseases with varying severity ranging from those causing systemic malignancy such as Multiple Myeloma, to clinically benign pathologies, such as solitary plasmacytoma of bone. Solitary plasmacytoma is a rare localized form of neoplastic proliferation of monoclonal plasma cells that produce a single osseous lesion. It accounts for 3% of all plasma cell malignancies, with the most common location being the axial skeleton. A literature review reveals very few reported cases of solitary plasmacytoma in the foot and ankle. We searched through multiple databases including the Journal of Foot and Ankle Surgery as well as PubMed Central using key words such as “plasmacytoma” and “plasma cell dyscrasia.” Involvement of the lower extremity is extremely rare. We report a case of plasmacytoma of the Talus with subsequent pathologic fracture, highlighting the unusual clinical features of presentation while exploring diagnostic modalities for solitary plasmacytoma in the foot. To our knowledge, only one other plasmacytoma findings in the foot and ankle have previously presented with a pathologic fracture. This case report shows radiographic and advanced imaging findings.