Abstract

Graves' disease is the most common autoimmune disease in hyperthyroidism. Sarcoidosis is an inflammatory granulomatousdisease of unknown cause. The association of the two diseases has rarely been reported in the literature. We report a new caseof newly diagnosed sarcoidosis in a patient followed for Graves' disease. This is an original case of Graves' disease, the courseof which was marked by the onset of active sarcoidosis presented as Lofgren's syndrome complicated by hypercalcemia. Givenits rarity and the lack of a causal link, the association between Graves' disease and sarcoidosis may be a mere coincidence. Morestudies could allow us to understand more common etiopathogenic mechanisms since both are chronic inflammatory diseases.

Highlights

  • Graves' disease is the most common autoimmune disease in hyperthyroidism

  • We report a new case of newly diagnosed sarcoidosis in a patient followed for Graves' disease

  • This is an original case of Graves' disease, the course of which was marked by the onset of active sarcoidosis presented as Löfgren's syndrome complicated by hypercalcemia

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Summary

Introduction

Graves' disease is the most common autoimmune disease in hyperthyroidism. Sarcoidosis is an inflammatory granulomatous disease of unknown cause. This is an original case of Graves' disease, the course of which was marked by the onset of active sarcoidosis presented as Löfgren's syndrome complicated by hypercalcemia. More studies could allow us to understand more common etiopathogenic mechanisms since both are chronic inflammatory diseases. Graves' disease is the most common autoimmune disease in hyperthyroidism.

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