A randomized controlled trial on comparison of colon cleansing for colonoscopy bowel preparation using one-day or two-day regimen methods

Abstract

BackgroundAdequate bowel cleansing prior to colonoscopy is important to achieve clearer view of the bowel and ease diagnosis. ObjectiveThis study was performed to compare colon cleansing prior to colonoscopy using one-day and two-day regimens. MethodThis study is a randomized controlled clinical trial, the patients were randomly allotted in one-day or two-day colon cleansing groups Polyethylene glycol was used as a laxative agent and colonoscopy was performed either on one-day following the bowel cleansing or non-next day (two-day) after the bowel cleansing. Statistical analysis was performed by SPSS software (version 22). ResultsOverall, the two groups had 52 patients and were not significantly different in terms of age and gender. The mean duration of colonoscopy in the one-day group was 9.44 min and in the two-day diet group was 10.5 min, which was also not significantly different, P = 0.098. Total colon cleansing in one-day was acceptable in 94.2% and unacceptable in 5.8% patients. The two-day clearance rate was 80.8% and unacceptable clearance 19.2% patients, which was statistically significant, p = 0.038. ConclusionThe total colon cleansing was better in one-day regime group. The two groups did not different in terms of side effects and these effects were not associated with age and the gender of the patients.