A Randomized Controlled Trial of the Effect of Pertussis Vaccineson Atopic Disease

Abstract

1. Nilsson L, 2. Kjellman M, 3. Bjorksten B (1998) Arch Pediatr Adolesc Med. 152:734–738. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] #### Purpose of the Study The development of allergy has been linked to a variety of factors, including genetic predisposition, environment, smoke exposure, and infection. Pertussis is known to act as an adjuvant to the development of sensitization in laboratory animal models. This observation was the background for this study, the purpose of which was to determine if pertussis vaccination was associated with allergen sensitization and the development of allergic disease in children. ##### Study Population The 669 children participating were part of the larger Swedish vaccine trial. This study was a randomized, double-blinded comparison of the … [1]: {openurl}?query=rft.jtitle%253DArchives%2Bof%2BPediatrics%2Band%2BAdolescent%2BMedicine%26rft.stitle%253DArch%2BPediatr%2BAdolesc%2BMed%26rft.issn%253D0002-922X%26rft.aulast%253DNilsson%26rft.auinit1%253DL.%26rft.volume%253D152%26rft.issue%253D8%26rft.spage%253D734%26rft.epage%253D738%26rft.atitle%253DA%2BRandomized%2BControlled%2BTrial%2Bof%2Bthe%2BEffect%2Bof%2BPertussis%2BVaccines%2Bon%2BAtopic%2BDisease%26rft_id%253Dinfo%253Adoi%252F10.1001%252Farchpedi.152.8.734%26rft_id%253Dinfo%253Apmid%252F9701130%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/archpedi.152.8.734&link_type=DOI [3]: /lookup/external-ref?access_num=9701130&link_type=MED&atom=%2Fpediatrics%2F104%2FSupplement_2%2F358.1.atom [4]: /lookup/external-ref?access_num=000075126500003&link_type=ISI