A randomized controlled clinical trial of acoustic resonance combined with systemic steroid therapy for sudden hearing loss

Abstract

Objective:To study the short-term and long-term therapeutic effect of acoustic resonance combined with systemic steroid therapy in treatment of Sudden hearing loss (SHL).Method:Clinical data of 128 patients with SHL were analyzed in the randomized controlled trial. Patients were divided into study group (68 cases) and control group (60 cases). Patients in control group received steroid therapy and conventional drug therapy, while study group received acoustic resonance therapy combined with systemic steroid therapy and conventional drug therapy.Result:The total effective rate of study group and control group was 66.18% and 65.00% respectively at the end of treatment; the total effective rate of study group and control group was 72.06% and 70.00% 4 weeks after treatment; the total efficiency of study group and control group was 73.53% and 68.33% respectively 8 weeks after treatment. The total effective rate of study group was not significantly higher than that of the control group in the three periods (P> 0.05). But the PTA significantly improved in study group 4 weeks and 8 weeks after treatment [(43.87±16.73)dB, (40.96±17.11)dB], while the PTA of control group is (50.89±18.41)dB, (48.93±17.84)dB (P< 0.05), and no serious adverse events were happened during treatments and after treatments.Conclusion:Acoustic resonance combined with systemic steroid therapy can significantly improve the therapeutic effect of SHL with no obvious side effects, which is worth clinical promotion.