Abstract

Urinary tract infections (UTIs) are one of the most common reasons for antibiotic prescriptions among women worldwide. UTIs are also associated with intra- and postoperative catheterization, which is an essential component of many gynecological surgical procedures, including midurethral sling (MUS) placement. The aim of this study was to compare the incidence of UTI subsequent to a MUS procedure. The study involved 562 female patients who underwent MUS procedures due to stress urinary incontinence (SUI). Patients were assigned in a 1:1 ratio to two study groups: patients receiving 500 mg of ciprofloxacin three times a day for 3 consecutive days after surgery or patients receiving 5 mL of Canephron taken orally three times a day for 3 weeks. After analyzing the collected data, it was found that in the group of patients receiving ciprofloxacin, 29 women (10.98%) had a UTI, whereas in the group of patients receiving Canephron, 36 women (13.64%) had a UTI within 6 months after the patient’s MUS procedure. No statistically significant difference between the two groups was noted. Postoperative prophylaxis with a phytodrug can be perceived as an attractive option in the reduction of antibiotic consumption among female patients after a MUS procedure.

Highlights

  • Urinary tract infections (UTIs) are one of the most common reasons for antibiotic prescriptions among women

  • UTIs are associated with intra- and postoperative catheterization, which is an essential component of many gynecological surgical procedures, including midurethral sling (MUS) placement

  • Postoperative prophylaxis with a phytodrug can be perceived as an attractive option in the reduction of antibiotic consumption among female patients after a MUS procedure

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Summary

Introduction

Urinary tract infections (UTIs) are one of the most common reasons for antibiotic prescriptions among women. It has been observed that 27% of women will develop at least one culture-confirmed recurrence within the 6 months following the initial infection and therapy [1]. UTIs account for about 40% of hospital-acquired infections, and 80% of these infections are associated with urinary catheters compared with only 3–4% per year for women in the general population [3,4]. This pathology is known as a catheter-associated UTI (CAUTI), and it has a daily estimated risk of 3–7% in the acute care setting [5]. Decreasing the duration of catheterization significantly lowers this risk, it can still be as high as 38% in the first 6 weeks following catheter removal, even among women undergoing relatively short-term catheterization for elective gynecological surgery [7,8]

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