Abstract
A radioimmunological method for determining prolactin in human blood plasma, which is extremely accurate and rather simple, has been developed, standardized, and statistically evaluated in our laboratory. The basal prolactin ontent was determined in healthy persons of both sexes. The average level of the hormone in the blood of women in the follicular phase of the menstrual cycle was higher than cin men, which agrees with the data of other authors [8, 9] and is evidently due to the positive action of estrogens on the secretion of prolactin in connection with the inhibition of the hypothalamic prolactin-releasing factor. In 57% of men with idiopathic oligospermia, the prolactin level is higher than the average, which may be evidence of the important role of this hormone in the pathogenesis of male infertility.
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