Abstract
The preparation of a highly specific antiserum for betamethazone is described giving details of the preparation of the immunogen betamethazone-3- (O-carboxymethyl) oxime-BSA conjugate, immunisation schedule, antibody titres and the cross reactions of related physiological and synthetic corticosteroids. Details of a radioimmunoassay of betamethazone with and without extraction are given showing negligible cross-reaction with cortisol. Concentrations in peripheral human venous plasma before, during, and after an intravenous infusion of betamethazone used to induce labour are also reported.
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