Abstract

Wrinkles or rhytids are a part of the natural ageing process of the human body. Long pulsed Nd: YAG laser (LPND) promotes dermal collagen remodelling without damaging the superficial layers and hence reduce periorbital wrinkles. Patients seeking treatment for periorbital wrinkles, and willing to participate in the study were included. Wrinkles were graded on the basis of wrinkle severity score (WSS) at baseline and one month after 4 monthly sessions of treatment. The 1064nm LPND was employed with settings of: spot size - 10mm, on time - 40 to 50 ms, fluence - 30 to 50 J/cm and frequency - 1 Hz. Three overlapping passes were done on both sides of the face. Outcome was measured by subjects, investigator and a blinded dermatologist. Appropriate statistical analysis was done. Twenty eight sites were treated in 14 subjects. Male to female ratio was 3:4. Their mean age was 45.86 ± 8.75. Mean WSS by investigator at baseline was 3.18 ± 1.188 and at the end of treatment was 1.89 ± 1.031 (p = 0.001). Mean WSS by the blinded dermatologist was 3.18 ± 1.188 at baseline and 2.43 ± 1.034 at end of the treatment (p =0.001). The subject’s degree of satisfaction was found to be 2.96 ± 1.036. There were no significant adverse events. LPND for periorbital wrinkles is both patient and physician friendly, offering maximum results with minimal discomfort and downtime. This modality needs further exploration in the treatment of periorbital wrinkles in the Indian population.

Highlights

  • Wrinkles or rhytids are a part of the natural ageing process of the human body

  • Mean wrinkle severity score (WSS) grading by the blinded dermatologist was 3.18 ± 1.188 at baseline and 2.43 ± 1.034 at end of the treatment (p =0.001) (Table 4)

  • Our results indicate a good improvement of 41% according to the investigator and 24% according to the blinded dermatologist

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Summary

Introduction

Wrinkles or rhytids are a part of the natural ageing process of the human body. Long pulsed Nd: YAG laser (LPND) promotes dermal collagen remodelling without damaging the superficial layers and reduce periorbital wrinkles. Mean WSS by investigator at baseline was 3.18 ± 1.188 and at the end of treatment was 1.89 ± 1.031 (p = 0.001). Mean WSS by the blinded dermatologist was 3.18 ± 1.188 at baseline and 2.43 ± 1.034 at end of the treatment (p =0.001). Conclusion: LPND for periorbital wrinkles is both patient and physician friendly, offering maximum results with minimal discomfort and downtime. This modality needs further exploration in the treatment of periorbital wrinkles in the Indian population. As face is a site of aesthetic concern, patients look for a simple yet effective method to reduce wrinkling. The adverse effects like epidermal denudation and thermal injury have posed a significant challenge and reduced the amount of patients opting for this modality. Non ablative lasers are safer and give almost similar results with lesser undesirable consequences

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