A putative role of dietary omega-3 polyunsaturated fatty acids in oxidative modification of low density lipoprotein

Abstract

Oxidative modification of low density lipoprotein is a cell-mediated process that is believed to increase the atherogenicity of the particle. There is a growing interest in measures that could inhibit this process because of their potential impact on the risk of atherosclerotic disease. It is suggested that diets rich in polyunsaturated fatty acids of the omega-3 series inhibit cell-induced oxidative modification of low density lipoprotein (LDL), thereby contributing to the prevention of atherosclerosis.