Abstract

3D bioprinting is an innovative method of manufacturing three-dimensional tissue-like structures. The method is based on a layer-by-layer deposition of biocompatible materials successively forming a scaffold for living cells. The technology allows to fabricate complicated tissue morphology, including vascular-like networks. The range of potential applications of 3D bioprinting is immense: from drug testing, across regenerative medicine, to organ transplantation. In this paper, we describe a prototype of a 3D bioprinter utilizing gelatin methacrylate (GelMA) doped with a photoinitiator as the printing substance. Biological requirements for the material, its synthesis and application adequacy for the bioprinting process are discussed. Technical details of the mechanical construction of the bioprinter and its control system are presented

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