Abstract

BackgroundThe Modified Early Warning Score (MEWS) was developed to timely recognise clinically deteriorating hospitalised patients. However, the ability of the MEWS in predicting serious adverse events (SAEs) in a general hospital population has not been examined prospectively. The aims were to (1) analyse protocol adherence to a MEWS protocol in a real-life setting and (2) to determine the predictive value of protocolised daily MEWS measurement on SAEs: death, cardiac arrests, ICU-admissions and readmissions.MethodsAll adult patients admitted to 6 hospital wards in October and November 2015 were included. MEWS were checked each morning by the research team. For each critical score (MEWS ≥ 3), the clinical staff was inquired about the actions performed. 30-day follow-up for SAEs was performed to compare between patients with and without a critical score.Results1053 patients with 3673 vital parameter measurements were included, 200 (19.0%) had a critical score. The protocol adherence was 89.0%. 18.2% of MEWS were calculated wrongly. Patients with critical scores had significant higher rates of unplanned ICU admissions [7.0% vs 1.3%, p < 0.001], in-hospital mortality [6.0% vs 0.8%, p < 0.001], 30-day readmission rates [18.6% vs 10.8%, p < 0.05], and a longer length of stay [15.65 (SD: 15.7 days) vs 6.09 (SD: 6.9), p < 0.001]. Specificity of MEWS related to composite adverse events was 83% with a negative predicting value of 98.1%.ConclusionsProtocol adherence was high, even though one-third of the critical scores were calculated wrongly. Patients with a MEWS ≥ 3 experienced significantly more adverse events. The negative predictive value of early morning MEWS < 3 was 98.1%, indicating the reliability of this score as a screening tool.

Highlights

  • Serious adverse events (SAEs) in hospitalised patients are preceded by signs of clinical deterioration in up to 80% of the patients [1]

  • Patients with critical scores had significant higher rates of unplanned intensive care unit (ICU) admissions [7.0% vs 1.3%, p < 0.001], in-hospital mortality [6.0% vs 0.8%, p < 0.001], 30-day readmission rates [18.6% vs 10.8%, p < 0.05], and a longer length of stay [15.65 (SD: 15.7 days) vs 6.09 (SD: 6.9), p < 0.001]

  • Specificity of Modified Early Warning Score (MEWS) related to composite adverse events was 83% with a negative predicting value of 98.1%

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Summary

Introduction

Serious adverse events (SAEs) in hospitalised patients are preceded by signs of clinical deterioration in up to 80% of the patients [1]. RRSs consist of two different components: an afferent limb consisting of track and trigger systems (TTS) such as Modified Early Warning Score (MEWS) and an efferent limb, a rapid intervention team (RIT) consisting of trained ICU personnel who will deliver immediate treatment to deteriorating patient at the bedside. Introduced in 1997 by Morgan et al the TTS functions as the afferent limb and is designed to detect deterioration early [9] Since this first introduction multiple early warning bedside monitoring tools have been developed and implemented internationally [10, 11]. These TTSs are used to detect deterioration and call upon a team to monitor and treat patients to prevent further deterioration [12]. The aims were to (1) analyse protocol adherence to a MEWS protocol in a real-life setting and (2) to determine the predictive value of protocolised daily MEWS measurement on SAEs: death, cardiac arrests, ICU-admissions and readmissions.

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