Abstract
Introduction: The impact of coronary artery disease (CAD) on the later development of dementia is not well studied globally. Therefore, this study aims to determine the long-term risk of dementia using a mobile application-based tool in addition to elucidating the contributing factors among CAD patients. Protocol: This cross-sectional study collected data from 285 stable CAD patients admitted to the “Ibrahim Cardiac Hospital and Research Institute” for coronary revascularization from August 2019 to July 2020. The patients were recruited using a convenient sampling technique due to economic and logistical issues. Data were collected through a face-to-face interview using a pretested semi-structured questionnaire. Physical parameters (blood pressure and anthropometry) were measured while maintaining the adequate privacy of the patients. The biochemical parameters analyzed by the hospital lab were also collected. The next phase of this study involves the use of a mobile application that uses the Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) dementia risk score, to determine the risk factors associated with dementia. In addition, a descriptive statistical and inferential analysis will also be performed to determine the key contributing risk factors linked to the development of dementia. Ethics and dissemination: The study has been reviewed and approved by the Ethical Review Committee of Bangladesh University of Health Sciences. The results will be actively disseminated through peer-reviewed journals, conference presentations, social media, online news portal, the internet, and various community/stakeholder engagement activities. Conclusion: As a baseline study of the country, this study will fill a key knowledge gap in the pathway to the development of better interventions for dementia in Bangladesh. Outcomes from this study will also help with raising awareness on the association of mental health-related issues with cardiovascular diseases so that an improved cardiac rehabilitation program can be implemented in Bangladesh.
Highlights
The impact of coronary artery disease (CAD) on the later development of dementia is not well studied globally
The CAIDE risk score based mobile application tool has never previously been applied within the Bangladeshi population and we will pre-test it in a sample of CAD patients before the final application
Studies on dementia risk and its associated factors is scarce in Bangladesh
Summary
Any reports and responses or comments on the article can be found at the end of the article. Keywords Risk of dementia, coronary artery disease, CAIDE score, risk factors, Bangladesh. We have clarified the tool name and source more precisely according to the suggestion from the reviewer. We have changed the timeline as suggested by the reviewer. People with coronary artery diseases (CADs) have a higher chance of developing dementia because they have already been exposed to some kind of vascular damage[10]. Numerous vascular risk factors like systolic hypertension and diabetes mellitus are already known to be associated with cognitive impairments[11]. Systolic hypertension is an imperative modifiable risk factor for late-life cognitive impairment that can increase the risk of vascular dementia[12]
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