A prospective study to evaluate the repigmentation in vitiligo after noncultured epidermal cell transplant followed by puva

Abstract

To evaluate the repigmentation with non-cultured epidermal cell suspension followed by PUVA in patients with stable vitiligo.A prospective study conducted at the department of Dermatology, Venerology, Leprosy of Rajah Muthiah Medical College and Hospital. 26 cases of stable vitiligo were treated with non-cultured epidermal cell suspension followed by PUVA and were reviewed for a period of 20 weeks.The results were assessed subjectively. 9 (34.6%) patients showed excellent response to our therapy, 7 (26.9%) patients had good response, 5 (19.3%) patients showed fair response and 3 (11.5%) showed very poor response. 17 (65%) patients showed a very good colour match when compared with the surrounding skin and 1 (3.8%) patients showed donor site scarring.Epidermal non cultured cell suspension followed by PUVA is a relatively safe method with superior quality of repigmentation.