A prospective study to correlate serum progesterone levels and clinical pregnancy outcome in frozen embryo transfer cycles

Abstract

Methods: Total 100 patients were included in the study and divided into two groups (A and B). Blood levels of p4 were measured when beginning progesterone and on the day of Frozen embryo transfer (FET) in one group and were supplemented if levels were less than 10 ng/mL. No measurement of serum p4 was undertaken in the other group (B). Statistical tests like chi square test and Mann-Whitney test were applied and SPSS version 23 was used. Outcome: Clinical pregnancy outcome. Results: Clinical pregnancy rate was 32.69% in group A vs 24% in the other group which is non-significant. Conclusion: Serum p4 should be between 1.5 and 24 ng/mL on the starting day for a positive result. Level in blood on the day of starting progesterone to obtain a positive clinical pregnancy was 0.21 ng/mL and should not exceed 0.96 ng/mL.