Abstract
Objective: To evaluate the quality of life (QoL) after palliative surgery of patients with advanced breast or gastrointestinal malignancies Methods: Quality of Life (QoL) of 32 patients with advanced breast or gastrointestinal cancer (Stage IIIB up to Stage IV) was evaluated before surgery (baseline), then 7 and 30 days after surgery using the Medical Outcomes Study Short form (SF-36v2™ Questionnaire). Statistical significance of the difference in outcomes was tested using the two-tailed T-test at 95% CI. Results: Preoperatively, the patients scored poorly (scores below the average mean of 50) in all 8 subscales of the SF-36v2™. Seven days after a palliative surgery, patients showed significant improvement in all subscales except Vitality and Social Functioning. The patients experienced statistically significant changes in quality of life subscale scores on Physical Functioning, Role-Physical, Bodily Pain, General Health, Role Emotional, and Mental Health after surgery. A significant change in all subscales occurred 30 days after surgery compared to the baseline and 7 days post-op. Conclusions: While patients with advanced malignancy experienced problems with quality of life preoperatively, they improved postoperatively but not to the level of a normal person. Key words: quality of life, advanced breast cancer, advanced gastrointestinal malignancy
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