Abstract
Background: Systemic uptake of hypotonic fluid during irrigation performed at the time of Transurethral Resection of the Prostate (TURP) may cause electrolyte changes including sodium, potassium and calcium. The present study was aimed to assess the degree of sodium changes during Transurethral Resection of Prostate (TURP).
 Methods: 50 males aged 54 to 86 years, presented for TURP, were enrolled in the study with ASA classification of I to IV grades. Glycine 1.5% was used with height of irrigation kept at 60 cm. One day preoperatively and one hour postoperative, levels of serum sodium were measured for all the patients.
 Results: Spinal anaesthesia was given in 31 patients, whereas 19 patients were managed under general anaesthesia, with mean duration time being 72.42 ± 24.77min. The mean size of the resected prostate was 54.82 ± 25.04g. 58% patients developed mild hyponatremia, 4% had asymptomatic moderate hyponatremia and no patient developed severe hyponatremia or TURP Syndrome. The systemic diseases like hypertension, DM, or IHD found to be insignificant.
 Conclusion: TURP was associated with a high incidence of asymptomatic mild hyponatremia. Duration of operation was one of the most important factors.
Highlights
From past 60 years, the benign prostatic hyperplasia (BPH) remains a common illness in men
Ethical approval was obtained from the ACH Ethics and Internal Review Board (IBR) committee. 50 male patients aged 54 – 86 years presented for Transurethral Resection of Prostate (TURP) were enrolled in the study with American Society of Anesthesiologists (ASA) classification of grade I and IV
Spinal anaesthesia was given to 31 patients (62%) and 19 (38%) patients were subjected to general anaesthesia
Summary
From past 60 years, the benign prostatic hyperplasia (BPH) remains a common illness in men. Surgical treatment of BPH involves the Transurethral resection of the prostate (TURP), which is anurological intervention, done under spinal or general anaesthesia using endoscopy. It is being advocated as the treatment of choice in 95% cases with simple prostatectomy, being more secure and effective than open prostatectomy [4,5,6,7]. Acute hyponatremia is a serious condition that occurs with serum sodium concentration decreased to a level of 115–120 mEq/L [16]. Systemic uptake of hypotonic fluid during irrigation performed at the time of Transurethral Resection of the Prostate (TURP) may cause electrolyte changes including sodium, potassium and calcium.
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