A Prospective Study on Bacterial Isolation from Diabetic Foot Ulcer in Department of Surgery

Abstract

Background: There are various wound classification systems to assess the severity of diabetic foot ulcer and involve different factors specifically depth, site, presence of neuropathy, ischemia etc. Wagner’s system classification is the most widely used in grading of diabetic foot ulcers. Methods: The case study was carried out in the Department of Surgery, Geetanjali Medical College and Hospital, Udaipur. Results: 173 cases were enrolled in study and grade-3 Wagner’s ulcers were predominant. Males were predominant. Peripheral arterial disease was more common than peripheral neuropathy and both were found significantly associated with development of ulcers. Methicillin resistant Staphylococcus aureus and Klebsiella pneumoniae were most common isolates. MRSA exhibited maximum sensitivity to vancomycin, clindamycin and linezolid. Gram negative isolates exhibited maximum sensitivity to meropenems, piperacillin-tazobactam. Conclusions: This study conclude that prospective multicenter studies are required to assess the appropriate antibiotic regimen in diabetic foot ulcers and proper management of antibiotics must be started to decrease the incidence and development of MDR organisms.