A PROSPECTIVE STUDY OF ARTHROSCOPIC DEBRIDEMENT COMBINED WITH PLATELET RICH PLASMA INJECTION IN EARLY OSTEOARTHRITIS OF KNEE JOINT

Abstract

Background Osteoarthritis (OA) of the knee joint being one of the leading causes of musculoskeletal disability, has also shown increased prevalence in the Indian population. It has been observed that with careful patient selection arthroscopic debridement can provide good symptomatic relief. In the recent years, autologous platelet-rich plasma has emerged as a better treatment option. We propose that combining these two procedures together will give better results in some cases of early OA. To determine theObjectives efcacy and functional outcome of arthroscopic debridement along with intra-articular inltration of autologous platelet rich plasma in early OA knee. To assess the safety of usage of intra-articular inltration of platelet rich plasma in early OA knee. Materials and methods A prospective study conducted for a period of 24 months among 55 patients with early osteoarthritis at SSIMS & RC hospital, Davanagere, Karnataka. Under aseptic precautions, arthroscopic debridement of knee was done, after debridement 4 ml platelet concentrate was injected into knee joint. The pain assessment was done by Visual Analogue Scale (VAS), and the course of disease and effectiveness of therapy was assessed by measurement of Western Ontario and McMaster Universities Arthritis Index (WOMAC), before procedure and at 6 weeks, 3 months, and 6 months after procedure. Osteoarthritis of knee joint was affected on both sides in about 41.8%. The mean VAS score at baseline was 6.54Results ±0.719. The mean WOMAC score at baseline was 71.07 ±3.826. On comparing the mean baseline with the variation in each follow up, we found statistically signicant relation, suggesting that there was improvement in the condition of the participants. Conclusion The study found that arthroscopic debridement with intra-articular inltration of platelet rich plasma in early osteoarthritis knee signicantly reduced the pain, as the mean values of VAS score decreased drastically, and also improved the condition of the participants.