A prospective randomized controlled trial: laparoscopic Roux-en-Y gastric bypass vs. laparoscopic mini gastric bypass

Abstract

Objective To evaluate the clinical efficacy and safety of laparoscopic Roux-en-Y gastric bypass (LRYGB) vs. laparoscopic mini gastric bypass (LMGB). Methods Forty-five patients diagnosed as having obesity were included in this study at our institution, and randomized into two groups: LRYGB group (n=23) and LMGB group (n=22). Data including gender, age, weight, height, body mass index, operative duration, postoperative hospital stay, surgical complications, operation time, hypertension, postoperative blood sugar and glycosylated hemoglobin were analyzed. Results There were no significant differences between the two groups with respect to gender, age, weight, height and body mass index (BMI). The operation time in LRYGB group was significantly longer than that in LMGB group [(162.5±35.4) vs. (120.7±39.8) min, P=0.036]. The postoperative hospit stay in LRYGB group was significantly longer than that in LMGB group [(9.2±2.3) vs. (7.4±2.5) d, P=0.042]. There were no statistically significant differences between the two groups in terms of complications (P=0.801). The levels of waistline, BMI, hypertension-related parameters, homeostasis model of assessment for insulin resistence index (HOMA-IR) and hemoglobin A1c (HbA1c) within the postoperative 12 months were improved in two groups, but there was no significant difference between the two groups. Conclusion This prospective randomized controlled study showed that LRYGB and LMGB may result in satisfactory and safe effects for the treatment of obesity. The operation time of LMGB was shorter and the postoperative recovery was faster. Key words: Laparoscopic mini gastric bypass; Laparoscopy; Obesity